RT Journal Article
T1 A EAACI drug allergy interest group survey on how European allergy specialists deal with β-lactam allergy.
A1 Torres, Maria Jose
A1 Celik, Gulfem Elif
A1 Whitaker, Paul
A1 Atanaskovic-Markovic, Marina
A1 Barbaud, Annick
A1 Bircher, Andreas
A1 Blanca, Miguel
A1 Brockow, Knut
A1 Caubet, Jean-Christoph
A1 Rodrigues-Cernadas, Josefina
A1 Chiriac, Anca
A1 Demoly, Pascal
A1 Garvey, Lene Heise
A1 Merk, Hans F
A1 Mosbech, Holger
A1 Nakonechna, Alla
A1 Romano, Antonino
K1 Europe
K1 Allergy
K1 Diagnosis
K1 Guidelines
K1 β-Lactam
AB An accurate diagnosis of β-lactam (BL) allergy can reduce patient morbidity and mortality. Our aim was to investigate the availability of BL reagents, their use and test procedures in different parts of Europe, as well as any differences in the diagnostic workups for evaluating subjects with BL hypersensitivity. A survey was emailed to all members of the EAACI Drug Allergy Interest Group (DAIG) between February and April 2016, and the questionnaire was meant to study the management of suspected BL hypersensitivity. The questionnaire was emailed to 82 DAIG centres and answered by 57. Amoxicillin alone or combined to clavulanic acid were the most commonly involved BL except in the Danish centre, where penicillin V was the most frequently suspected BL. All centres performed an allergy workup in subjects with histories of hypersensitivity to BL: 53 centres (93%) followed DAIG guidelines, two national guidelines and two local guidelines. However, there were deviations from DAIG recommendations concerning allergy tests, especially drug provocation tests. A significant heterogeneity exists in current practice not only among countries, but also among centres within the same country. This suggests the need to re-evaluate, update and standardize protocols on the management of patients with suspected BL allergy.
PB Wiley
YR 2018
FD 2018-08-22
LK http://hdl.handle.net/10668/13417
UL http://hdl.handle.net/10668/13417
LA en
NO Torres MJ, Celik GE, Whitaker P, Atanaskovic-Markovic M, Barbaud A, Bircher A, et al. A EAACI drug allergy interest group survey on how European allergy specialists deal with β-lactam allergy. Allergy. 2019 Jun;74(6):1052-1062
NO Institute of Health “Carlos III” of the Ministry of Economy and Competitiveness (grants co-funded by European Regional Development Fund (ERDF), Grant/Award Number: ARADyAL RD16/0006/0001, PI15/01206, RIRAAF RD12/0013/0001).
DS RISalud
RD Apr 6, 2025