TY - JOUR AU - Trigos, Anna Sofia AU - Pasam, Anupama AU - Banks, Patricia AU - Wallace, Roslyn AU - Guo, Christina AU - Keam, Simon AU - Thorne, Heather AU - kConFab AU - Mitchell, Catherine AU - Lade, Stephen AU - Clouston, David AU - Hakansson, Alexander AU - Liu, Yang AU - Blyth, Benjamin AU - Murphy, Declan AU - Lawrentschuk, Nathan AU - Bolton, Damien AU - Moon, Daniel AU - Darcy, Phil AU - Haupt, Ygal AU - Williams, Scott G AU - Castro, Elena AU - Olmos, David AU - Goode, David AU - Neeson, Paul AU - Sandhu, Shahneen PY - 2022 DO - 10.1136/jitc-2021-003744 UR - http://hdl.handle.net/10668/20159 T2 - Journal for immunotherapy of cancer AB - Aberrations in homologous recombination repair (HRR) genes are emerging as important biomarkers for personalized treatment in prostate cancer (PCa). HRR deficiency (HRD) could affect the tumor immune microenvironment (TIME), potentially contributing... LA - en KW - gene expression profiling KW - genetic markers KW - prostatic neoplasms KW - tumor microenvironment KW - Germ-Line Mutation KW - Humans KW - Immune Checkpoint Inhibitors KW - Male KW - Prostatic Neoplasms KW - Recombinational DNA Repair KW - Tumor Microenvironment TI - Tumor immune microenvironment of primary prostate cancer with and without germline mutations in homologous recombination repair genes. TY - research article VL - 10 ER -