RT Journal Article
T1 Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project.
A1 Bassetti, Matteo
A1 Giacobbe, Daniele R
A1 Vena, Antonio
A1 Trucchi, Cecilia
A1 Ansaldi, Filippo
A1 Antonelli, Massimo
A1 Adamkova, Vaclava
A1 Alicino, Cristiano
A1 Almyroudi, Maria-Panagiota
A1 Atchade, Enora
A1 Azzini, Anna M
A1 Carannante, Novella
A1 Carnelutti, Alessia
A1 Corcione, Silvia
A1 Cortegiani, Andrea
A1 Dimopoulos, George
A1 Dubler, Simon
A1 García-Garmendia, José L
A1 Girardis, Massimo
A1 Cornely, Oliver A
A1 Ianniruberto, Stefano
A1 Kullberg, Bart Jan
A1 Lagrou, Katrien
A1 Le Bihan, Clement
A1 Luzzati, Roberto
A1 Malbrain, Manu L N G
A1 Merelli, Maria
A1 Marques, Ana J
A1 Martin-Loeches, Ignacio
A1 Mesini, Alessio
A1 Paiva, José-Artur
A1 Peghin, Maddalena
A1 Raineri, Santi Maurizio
A1 Rautemaa-Richardson, Riina
A1 Schouten, Jeroen
A1 Brugnaro, Pierluigi
A1 Spapen, Herbert
A1 Tasioudis, Polychronis
A1 Timsit, Jean-François
A1 Tisa, Valentino
A1 Tumbarello, Mario
A1 van den Berg, Charlotte H S B
A1 Veber, Benoit
A1 Venditti, Mario
A1 Voiriot, Guillaume
A1 Wauters, Joost
A1 Montravers, Philippe
K1 Abdominal candidiasis
K1 Candida
K1 Candidemia
K1 Candidiasis
K1 ICU
K1 Incidence
AB The objective of this study was to assess the cumulative incidence of invasive candidiasis (IC) in intensive care units (ICUs) in Europe. A multinational, multicenter, retrospective study was conducted in 23 ICUs in 9 European countries, representing the first phase of the candidemia/intra-abdominal candidiasis in European ICU project (EUCANDICU). During the study period, 570 episodes of ICU-acquired IC were observed, with a cumulative incidence of 7.07 episodes per 1000 ICU admissions, with important between-center variability. Separated, non-mutually exclusive cumulative incidences of candidemia and IAC were 5.52 and 1.84 episodes per 1000 ICU admissions, respectively. Crude 30-day mortality was 42%. Age (odds ratio [OR] 1.04 per year, 95% CI 1.02-1.06, p  The cumulative incidence of IC in 23 European ICUs was 7.07 episodes per 1000 ICU admissions. Future in-depth analyses will allow explaining part of the observed between-center variability, with the ultimate aim of helping to improve local infection control and antifungal stewardship projects and interventions.
YR 2019
FD 2019-06-14
LK http://hdl.handle.net/10668/14118
UL http://hdl.handle.net/10668/14118
LA en
DS RISalud
RD Apr 8, 2025