RT Generic
T1 Incidence and risk factors of pharyngocutaneus fistula formation after total laryngectomy. Review
A1 Isabel Sanz-Sanchez, Cristina
A1 Kraemer-Baeza, Else
A1 Dolores Aguilar-Conde, Maria
A1 Flores-Carmona, Eva
A1 Emilio Cazorla-Ramos, Oscar
K1 Pharyngocutaneous fistula
K1 incidence
K1 radiotherapy
K1 risk factors
K1 total laryngectomy
K1 postlaryngectomy complications
K1 Predisposing factors
K1 Predictive factors
K1 Fistulization
K1 Complications
AB Introduction and objective: The pharyngocutaneous fistula is a troublesome complication after total laryngectomy, increasing morbidity and mortality. We aimed to determine the incidence of pharyngocutaneus fistula after total laryngectomy and to define the possible predictors for pharyngocutaneus fistula formation. Method: We conducted a review of 31 articles with a total of 1100 patients, to evaluate the incidence of fistula in patients with total laryngectomy and risks factors involved. Results: The overall incidence of pharyngocutaneus fistula is 22,3%, and ranges from 3 to 65%. The review revealed that prior radiation treatment was the most common antecedent, following this associated comorbidity, hypoalbuminemia, anemia, and history of tracheotomy prior to laryngectomy. Discussion: Among the series studied, there is significant heterogeneity in the results, because although irradiated patients have a greater number of pharyngostomas, in some studies no relationship was found, which could explain the association with other risk factors. Conclusions: The incidence of pharyngocutaneus fistula is very variable and there are a large number of risk factors involved, the most frequent is radiotherapy associated or not with chemotherapy.
PB Univ salamanca, ediciones
YR 2021
FD 2021-01-01
LK https://hdl.handle.net/10668/26913
UL https://hdl.handle.net/10668/26913
LA es
DS RISalud
RD Apr 4, 2025