TY - JOUR AU - Martinez-Chamorro, A AU - Moreno, A AU - Gómez-García, M AU - Cabello, M J AU - Martin, J AU - Lopez-Nevot, M Á PY - 2016 DO - 10.1111/cei.12786 UR - http://hdl.handle.net/10668/9891 T2 - Clinical and experimental immunology AB - Ulcerative colitis (UC) is one of the two major forms of inflammatory bowel disease, the aetiology of which remains unknown. Several studies have demonstrated the genetic basis of disease, identifying more than 130 susceptibility loci. The major... LA - en KW - MHC KW - autoimmunity KW - cell surface molecules KW - inflammation KW - molecular biology KW - Abscess KW - Adult KW - Age of Onset KW - Alleles KW - Amino Acid Sequence KW - Case-Control Studies KW - Colitis, Ulcerative KW - Female KW - Gene Expression KW - Gene Frequency KW - Genetic Predisposition to Disease KW - HLA-B27 Antigen KW - HLA-B52 Antigen KW - Haplotypes KW - Histocompatibility Antigens Class I KW - Humans KW - Male KW - Middle Aged KW - Models, Molecular KW - Odds Ratio KW - Polymorphism, Genetic KW - Protein Domains KW - Protein Isoforms KW - Sequence Alignment TI - MICA*A4 protects against ulcerative colitis, whereas MICA*A5.1 is associated with abscess formation and age of onset. TY - research article VL - 184 ER -