TY - JOUR AU - Pérez-Villegas, Eva M AU - Pérez-Rodríguez, Mikel AU - Negrete-Díaz, José V AU - Ruiz, Rocío AU - Rosa, Jose Luis AU - de Toledo, Guillermo Alvarez AU - Rodríguez-Moreno, Antonio AU - Armengol, José A PY - 2020 DO - 10.3389/fnana.2020.592797 SN - 1662-5129 UR - https://hdl.handle.net/10668/27379 T2 - Frontiers in neuroanatomy AB - Mutations in the human HERC1 E3 ubiquitin ligase protein develop intellectual disability. The tambaleante (tbl) mouse carries a HERC1 mutation characterized by cerebellar ataxia due of adult cerebellar Purkinje cells death by extensive autophagy. Our... LA - en KW - LTP KW - autophagy KW - dendritic spines KW - glutamatergic input KW - hippocampus KW - synapses TI - HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory. TY - research article VL - 14 ER -