RT Journal Article
T1 Value of [18F]FDG-PET/CT and CA125, serum levels and kinetic parameters, in early detection of ovarian cancer recurrence: Influence of histological subtypes and tumor stages.
A1 Palomar Muñoz, Azahara
A1 Cordero García, José Manuel
A1 Talavera Rubio, Mª Del Prado
A1 García Vicente, Ana Mª
A1 Pena Pardo, Francisco José
A1 Jiménez Londoño, Germán Andrés
A1 Soriano Castrejón, Ángel
A1 Aranda Aguilar, Enrique
AB To assess the diagnostic accuracy of CA125, its kinetic values and positron emission tomography/computed tomography with 2-deoxy-2-[F]fluoro-D-glucose ([F]FDG-PET/CT), in relation with tumor characteristics for suspected recurrence of ovarian cancer. To evaluate the performance of CA125-related parameters as a selection criteria to perform a [F]FDG-PET/CT.A retrospective analysis of 69 [F]FDG-PET/CT for suspected recurrence of ovarian cancer was performed. All patients had 2 measurements of CA125, before PET/CT, to calculate kinetic values, as CA125vel (CA125vel = [CA125a - CA125b]/time) and CA125dt (CA125dt = [log2 × time]/[logCA125a - CA125b]). Maximum standard uptake value (SUVmax) was calculated. The diagnostic accuracy was calculated for all the variables and the optimal cut-off value of each of them by the receiver-operating characteristics (ROC) analysis. All the tests were compared with tumor characteristics and clinical-radiological evolution during follow-up of at least 6 months.Fifty-five cases were diagnosed of recurrence (11 with CA125 
YR 2018
FD 2018
LK http://hdl.handle.net/10668/12405
UL http://hdl.handle.net/10668/12405
LA en
DS RISalud
RD Apr 6, 2025