TY  - JOUR
AU  - Lotta, Luca A
AU  - Gulati, Pawan
AU  - Day, Felix R
AU  - Payne, Felicity
AU  - Ongen, Halit
AU  - van de Bunt, Martijn
AU  - Gaulton, Kyle J
AU  - Eicher, John D
AU  - Sharp, Stephen J
AU  - Luan, Jian'an
AU  - De Lucia Rolfe, Emanuella
AU  - Stewart, Isobel D
AU  - Wheeler, Eleanor
AU  - Willems, Sara M
AU  - Adams, Claire
AU  - Yaghootkar, Hanieh
AU  - EPIC-InterAct Consortium
AU  - Cambridge FPLD1 Consortium
AU  - Forouhi, Nita G
AU  - Khaw, Kay-Tee
AU  - Johnson, Andrew D
AU  - Semple, Robert K
AU  - Frayling, Timothy
AU  - Perry, John R B
AU  - Dermitzakis, Emmanouil
AU  - McCarthy, Mark I
AU  - Barroso, Inês
AU  - Wareham, Nicholas J
AU  - Savage, David B
AU  - Langenberg, Claudia
AU  - O'Rahilly, Stephen
AU  - Scott, Robert A
PY  - 2016
DO  - 10.1038/ng.3714
UR  - https://hdl.handle.net/10668/24638
T2  - Nature genetics
AB  - Insulin resistance is a key mediator of obesity-related cardiometabolic disease, yet the mechanisms underlying this link remain obscure. Using an integrative genomic approach, we identify 53 genomic regions associated with insulin resistance...
LA  - en
KW  - Adipose Tissue
KW  - Animals
KW  - Blood Glucose
KW  - Body Mass Index
KW  - Cardiovascular Diseases
KW  - Case-Control Studies
KW  - Disease Models, Animal
KW  - Female
KW  - Genome-Wide Association Study
KW  - Genomics
KW  - Humans
KW  - Insulin Resistance
KW  - Male
KW  - Metabolic Diseases
KW  - Mice
KW  - Obesity
KW  - Phenotype
TI  - Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.
TY  - research article
VL  - 49
ER  -