TY  - JOUR
AU  - Verdugo-Sivianes, Eva M.
AU  - Carnero, Amancio
PY  - 2021
DO  - 10.3390/cancers13092226
UR  - http://hdl.handle.net/10668/4331
T2  - Cancers
AB  - Cell cycle progression is highly regulated by modulating the phosphorylation status of the retinoblastoma protein (pRB) and the other two members of the RB family, p107 and p130. This process is controlled by a balance in the action of kinases, such...
LA  - en
PB  - MDPI
KW  - RB family proteins
KW  - Pocket proteins
KW  - Cell cycle
KW  - Phosphatase PP1
KW  - Spinophilin
KW  - PPP1R9B
KW  - Cancer
KW  - Tumorigenesis
KW  - Retinoblastoma protein
KW  - Phosphorylation
KW  - Catalytic subunit
KW  - Cyclin-dependent kinases
KW  - Stem cell
KW  - Breast cancer
KW  - Holoenzymes
KW  - Proteína fosfatasa 1
KW  - Neoplasias
KW  - Carcinogénesis
KW  - Proteína de retinoblastoma
KW  - Fosforilación
KW  - Dominio catalítico
KW  - Quinasas ciclina-dependientes
KW  - Células madre
KW  - Neoplasias de la mama
KW  - Holoenzimas
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins::Tumor Suppressor Proteins::Retinoblastoma Protein
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Monoester Hydrolases::Phosphoprotein Phosphatases::Protein Phosphatase 1
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Phosphorylation
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Binding Sites::Catalytic Domain
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Substrate Specificity
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Cyclin-Dependent Kinases
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Holoenzymes
KW  - Medical Subject Headings::Anatomy::Respiratory System::Lung
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Interphase::G1 Phase
TI  - Role of the Holoenzyme PP1-SPN in the Dephosphorylation of the RB Family of Tumor Suppressors During Cell Cycle
TY  - review article
ER  -