TY  - JOUR
AU  - Doyle, Tomas
AU  - Dunn, David T
AU  - Ceccherini-Silberstein, Francesca
AU  - De Mendoza, Carmen
AU  - Garcia, Frederico
AU  - Smit, Erasmus
AU  - Fearnhill, Esther
AU  - Marcelin, Anne-Genevieve
AU  - Martinez-Picado, Javier
AU  - Kaiser, Rolf
AU  - Geretti, Anna Maria
PY  - 2015
DO  - 10.1093/jac/dkv243
SN  - 0305-7453
UR  - http://hdl.handle.net/10668/2506
T2  - The Journal of Antimicrobial Chemotherapy
AB  - OBJECTIVESThe aim of this study was to characterize the prevalence and patterns of genotypic integrase inhibitor (INI) resistance in relation to HIV-1 clade.METHODSThe cohort comprised 533 INI-naive subjects and 255 raltegravir recipients with...
LA  - en
PB  - Oxford University Press
KW  - Estudios de cohortes
KW  - Farmacorresistencia viral
KW  - Fármacos anti-VIH
KW  - Europa (continente)
KW  - Infecciones por VIH
KW  - VIH-1
KW  - Inhibidores de integrasa
KW  - Mutación Missense
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Drug Resistance, Microbial::Drug Resistance, Viral
KW  - Medical Subject Headings::Geographicals::Geographic Locations::Europe
KW  - Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Retroviridae Infections::Lentivirus Infections::HIV Infections
KW  - Medical Subject Headings::Organisms::Viruses::RNA Viruses::Retroviridae::Lentivirus::Lentiviruses, Primate::HIV
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Integrase Inhibitors
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Mutation, Missense
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents::Anti-Retroviral Agents::Anti-HIV Agents
TI  - Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades.
TY  - research article
ER  -