TY - JOUR AU - Fu, Accalia AU - Alvarez-Perez, Juan Carlos AU - Avizonis, Daina AU - Kin, Tatsuya AU - Ficarro, Scott B AU - Choi, Dong Wook AU - Karakose, Esra AU - Badur, Mehmet G AU - Evans, Lindsay AU - Rosselot, Carolina AU - Bridon, Gaelle AU - Bird, Gregory H AU - Seo, Hyuk-Soo AU - Dhe-Paganon, Sirano AU - Kamphorst, Jurre J AU - Stewart, Andrew F AU - James Shapiro, A M AU - Marto, Jarrod A AU - Walensky, Loren D AU - Jones, Russell G AU - Garcia-Ocana, Adolfo AU - Danial, Nika N PY - 2020 DO - 10.1038/s42255-020-0199-4 UR - https://hdl.handle.net/10668/26613 T2 - Nature metabolism AB - Chronic inflammation is linked to diverse disease processes, but the intrinsic mechanisms that determine cellular sensitivity to inflammation are incompletely understood. Here, we show the contribution of glucose metabolism to inflammation-induced... LA - en KW - Adolescent KW - Adult KW - Aged KW - Arginine KW - Aspartic Acid KW - Cell Survival KW - Citric Acid Cycle KW - Female KW - Glucose KW - Humans KW - Inflammation KW - Insulin-Secreting Cells KW - Male KW - Metabolomics KW - Middle Aged KW - Nitric Oxide KW - Pyruvate Carboxylase KW - Urea KW - Urea Cycle Disorders, Inborn KW - Young Adult TI - Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation. TY - research article VL - 2 ER -