RT Journal Article
T1 Bolus Calculator Reduces Hypoglycemia in the Short Term and Fear of Hypoglycemia in the Long Term in Subjects with Type 1 Diabetes (CBMDI Study).
A1 Vallejo-Mora, Maria Del Rosario
A1 Carreira, Monica
A1 Anarte, Maria Teresa
A1 Linares, Francisca
A1 Olveira, Gabriel
A1 Gonzalez-Romero, Stella
K1 Bolus calculator
K1 Hypoglycemia
K1 Multiple daily injections of insulin
K1 Psychology
K1 Type 1 diabetes
AB In a previous study we demonstrated improvement in metabolic control and reduction in hypoglycemia in people with type 1 diabetes on multiple daily injections, after having used a bolus calculator for 4 months. To demonstrate whether (1) extending its use (2) or introducing it in the control group, previously subjected to treatment intensification, could further improve metabolic control and related psychological issues. After the previous clinical trial, in which the subjects were randomized either to treatment with the calculator or to control group for 4 months, both groups used the calculator during an additional 4-month period. In the previous control group, after using the device, HbA1c did not improve (7.86% ± 0.87% vs. 8.01% ± 0.93%, P 0.215), although a significant decrease in postprandial hypoglycemia was observed (2.3 ± 2 vs. 1.1 ± 1.2/2 weeks, P 0.002). In the group in which the treatment was extended from 4 to 8 months, HbA1c did not improve either (7.61 ± 0.58 vs. 7.73 ± 0.65, P 0.209); however this group had a greater perceived treatment satisfaction (12.03 ± 4.26 vs. 13.71 ± 3.75, P 0.007) and a significant decrease in fear of hypoglycemia (28.24 ± 8.18 basal vs. 25.66 ± 8.02 at 8 months, P 0.026). The extension in the use of the calculator or its introduction in a previously intensified control group did not improve metabolic control, although it did confirm a decrease in hypoglycemic episodes in the short term, while the extension of its use to 8 months was associated with a reduction in fear of hypoglycemia and greater treatment satisfaction.
PB Mary Ann Liebert, Inc. Publishers
YR 2017
FD 2017-07-01
LK http://hdl.handle.net/10668/11285
UL http://hdl.handle.net/10668/11285
LA en
NO Vallejo Mora MDR, Carreira M, Anarte MT, Linares F, Olveira G, González Romero S. Bolus Calculator Reduces Hypoglycemia in the Short Term and Fear of Hypoglycemia in the Long Term in Subjects with Type 1 Diabetes (CBMDI Study). Diabetes Technol Ther. 2017 Jul;19(7):402-409
NO This project was partially funded by the Sociedad Andaluza de Endocrinología y Nutrición (SAEN). No other funding was received.
DS RISalud
RD Apr 7, 2025