RT Journal Article T1 Real-life management of patients with breakthrough cancer pain caused by bone metastases in Spain. A1 Ferrer Albiach, Carlos A1 Villegas Estévez, Francisco A1 López Alarcón, Mª Dolores A1 de Madariaga, María A1 Carregal, Alfonso A1 Arranz, Javier A1 Trinidad Martín-Arroyo, José M A1 Jiménez López, Antonio Javier A1 Sanz Yagüe, Almudena K1 bone metastases K1 breakthrough cancer pain K1 health-related quality of life K1 management K1 opioids K1 satisfaction AB Purpose: We aimed to explore the characteristics, and real-life therapeutic management of patients with breakthrough cancer pain (BTcP) caused by bone metastases in Spain, and to evaluate physicians' opinion of and satisfaction with prescribed BTcP therapy. Participants and methods: For the purposes of this study, an ad-hoc questionnaire was developed consisting of two domains: a) organizational aspects and care standards; b) clinical and treatment variables of bone metastatic BTcP patients. In addition, physicians' satisfaction with their prescribed BTcP therapy was assessed. Specialists collected data from up to five patients receiving treatment for BTcP caused by bone metastasis, all patients gave their consent to participate prior to inclusion. Results: A total of 103 cancer pain specialists (radiation oncologists [38.8%], pain specialists [33.0%], and palliative care (PC) specialists [21.4%]) were polled, and data on 386 BTcP patients with bone metastatic disease were collected. Only 33% of the specialists had implemented specific protocols for BTcP management, and 19.4% had established referral protocols for this group of patients. Half of all participants (50.5%) address quality of life and quality of care in their patients; however, only 27.0% did so from the patient's perspective, as they should do. Most patients had multiple metastases and were prescribed rapid-onset fentanyl preparations (71.2%), followed by immediate-release morphine (9.3%) for the treatment of BTcP. Rapid-onset fentanyl was prescribed more often in PC units (79.0%) than in pain units (75.9%) and radiation oncology units (61.1%) (p SN 1178-7090 YR 2019 FD 2019-07-12 LK http://hdl.handle.net/10668/14356 UL http://hdl.handle.net/10668/14356 LA en DS RISalud RD Apr 11, 2025