RT Journal Article
T1 Association between mental health comorbidity and health outcomes in type 2 diabetes mellitus patients
A1 Guerrero Fernández de Alba, Inmaculada
A1 Gimeno-Miguel, Antonio
A1 Poblador-Plou, Beatriz
A1 Gimeno-Feliu, Luis Andrés
A1 Ioakeim-Skoufa, Ignatios
A1 Rojo-Martínez, Gemma
A1 Forjaz, Maria João
A1 Prados-Torres, Alexandra
K1 Diabetes mellitus, type 2
K1 Mental health
K1 Comorbidity
K1 Substance-related disorders
K1 Chronic diseases
K1 Schizophrenia
K1 Diabetes Mellitus tipo 2
K1 Salud mental
K1 Comorbilidad
K1 Trastornos relacionados con sustancias
K1 Enfermedad crónica
K1 Esquizofrenia
AB Type 2 diabetes mellitus (T2D) is often accompanied by chronic diseases, including mental health problems. We aimed at studying mental health comorbidity prevalence in T2D patients and its association with T2D outcomes through a retrospective, observational study of individuals of the EpiChron Cohort (Aragón, Spain) with prevalent T2D in 2011 (n = 63,365). Participants were categorized as having or not mental health comorbidity (i.e., depression, anxiety, schizophrenia, and/or substance use disorder). We performed logistic regression models, controlled for age, sex and comorbidities, to analyse the likelihood of 4-year mortality, 1-year all-cause hospitalization, T2D-hospitalization, and emergency room visit. Mental health comorbidity was observed in 19% of patients. Depression was the most frequent condition, especially in women (20.7% vs. 7.57%). Mortality risk was higher in patients with mental health comorbidity (odds ratio 1.24; 95% confidence interval 1.16-1.31), especially in those with substance use disorder (2.18; 1.84-2.57) and schizophrenia (1.82; 1.50-2.21). Mental health comorbidity also increased the likelihood of all-cause hospitalization (1.16; 1.10-1.23), T2D-hospitalization (1.51; 1.18-1.93) and emergency room visit (1.26; 1.21-1.32). These results suggest that T2D healthcare management should include specific strategies for the early detection and treatment of mental health problems to reduce its impact on health outcomes.
PB Springer Nature
YR 2020
FD 2020-11-11
LK http://hdl.handle.net/10668/4039
UL http://hdl.handle.net/10668/4039
LA en
NO Guerrero Fernández de Alba I, Gimeno-Miguel A, Poblador-Plou B, Gimeno-Feliu LA, Ioakeim-Skoufa I, Rojo-Martínez G, et al. Association between mental health comorbidity and health outcomes in type 2 diabetes mellitus patients. Sci Rep. 2020 Nov 11;10(1):19583
DS RISalud
RD Apr 8, 2025