RT Journal Article
T1 Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review
A1 Rueda-Robles, Ascensión
A1 Rubio-Tomás, Teresa
A1 Plaza-Diaz, Julio
A1 Álvarez-Mercado, Ana I.
K1 Helicobacter pylori
K1 Diet
K1 Gastrointestinal microbiota
K1 Experimental models
K1 Therapeutic approaches
K1 Dysbiosis
K1 Peptic ulcer
K1 Dieta
K1 Microbioma gastrointestinal
K1 Modelos teóricos
K1 Conductas terapéuticas
K1 Disbiosis
K1 Gastritis
K1 Úlcera péptica
AB Helicobacter pylori (H. pylori) is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. This bacterium is responsible for long-term complications of gastric disease. The conjunction of host genetics, immune response, bacterial virulence expression, diet, micronutrient availability, and microbiome structure influence the disease outcomes related to chronic H. pylori infection. In this regard, the consumption of unhealthy and unbalanced diets can induce microbial dysbiosis, which infection with H. pylori may contribute to. However, to date, clinical trials have reported controversial results and current knowledge in this field is inconclusive. Here, we review preclinical studies concerning the changes produced in the microbiota that may be related to H. pylori infection, as well as the involvement of diet. We summarize and discuss the last approaches based on the modulation of the microbiota to improve the negative impact of H. pylori infection and their potential translation from bench to bedside.
PB MDPI
YR 2021
FD 2021-07-10
LK http://hdl.handle.net/10668/4075
UL http://hdl.handle.net/10668/4075
LA en
NO Rueda-Robles A, Rubio-Tomás T, Plaza-Diaz J, Álvarez-Mercado AI. Impact of Dietary Patterns on H. pylori Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review. Pathogens. 2021 Jul 10;10(7):875.
DS RISalud
RD Apr 7, 2025