RT Journal Article
T1 Basic Quality Controls Used in Skin Tissue Engineering
A1 Linares-Gonzalez, Laura
A1 Rodenas-Herranz, Teresa
A1 Campos, Fernando
A1 Ruiz-Villaverde, Ricardo
A1 Carriel, Víctor
K1 Skin tissue engineering
K1 Quality control
K1 Histological techniques
K1 Biochemical methods
K1 Biomechanical evaluation
K1 Enfermedades de la piel y tejido conjuntivo
K1 Control de calidad
K1 Técnicas histológicas
K1 Fenómenos bioquímicos
K1 Reacciones bioquímicas
AB Reconstruction of skin defects is often a challenging effort due to the currently limited reconstructive options. In this sense, tissue engineering has emerged as a possible alternative to replace or repair diseased or damaged tissues from the patient's own cells. A substantial number of tissue-engineered skin substitutes (TESSs) have been conceived and evaluated in vitro and in vivo showing promising results in the preclinical stage. However, only a few constructs have been used in the clinic. The lack of standardization in evaluation methods employed may in part be responsible for this discrepancy. This review covers the most well-known and up-to-date methods for evaluating the optimization of new TESSs and orientative guidelines for the evaluation of TESSs are proposed.
PB MDPI
YR 2021
FD 2021-09-30
LK http://hdl.handle.net/10668/4102
UL http://hdl.handle.net/10668/4102
LA en
NO Linares-Gonzalez L, Rodenas-Herranz T, Campos F, Ruiz-Villaverde R, Carriel V. Basic Quality Controls Used in Skin Tissue Engineering. Life . 2021 Sep 30;11(10):1033
DS RISalud
RD Apr 19, 2025