TY - JOUR AU - de Araujo Farias, Virgínea AU - O'Valle, Francisco AU - Serrano-Saenz, Santiago AU - Anderson, Per AU - Andrés, Eduardo AU - López-Peñalver, Jesús AU - Tovar, Isabel AU - Nieto, Ana AU - Santos, Ana AU - Martín, Francisco AU - Expósito, José AU - Oliver, F Javier AU - de Almodóvar, José Mariano Ruiz PY - 2018 DO - 10.1186/s12943-018-0867-0 UR - http://hdl.handle.net/10668/12839 T2 - Molecular cancer AB - We have recently shown that radiotherapy may not only be a successful local and regional treatment but, when combined with MSCs, may also be a novel systemic cancer therapy. This study aimed to investigate the role of exosomes derived from irradiated... LA - en KW - Abscopal effect KW - Annexin A1 KW - Bystander effect KW - Cell therapy KW - Experimental radiotherapy KW - Melanoma xenograft KW - Mesenchymal stem cells KW - Metastasis spread KW - Proteomic analysis KW - Animals KW - Cell Line, Tumor KW - Cell Proliferation KW - Combined Modality Therapy KW - Exosomes KW - Humans KW - MCF-7 Cells KW - Melanoma KW - Mesenchymal Stem Cell Transplantation KW - Mesenchymal Stem Cells KW - Mice, Inbred NOD KW - Mice, SCID KW - Neoplasm Metastasis KW - Proteomics KW - Radiotherapy KW - Treatment Outcome KW - Xenograft Model Antitumor Assays TI - Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci. TY - research article VL - 17 ER -