TY - JOUR AU - Yerbes, Rosario AU - Mora-Molina, Rocío AU - Fernández-Farrán, F Javier AU - Hiraldo, Laura AU - López-Rivas, Abelardo AU - Palacios, Carmen PY - 2022 DO - 10.1038/s41419-022-05346-y UR - http://hdl.handle.net/10668/19530 T2 - Cell death & disease AB - Oncogenic transformation leads to changes in glutamine metabolism that make transformed cells highly dependent on glutamine for anabolic growth and survival. Herein, we investigated the cell death mechanism activated in glutamine-addicted tumor cells... LA - en KW - Apoptosis KW - CASP8 and FADD-Like Apoptosis Regulating Protein KW - Caspase 8 KW - Glutamine KW - Receptors, TNF-Related Apoptosis-Inducing Ligand KW - TNF-Related Apoptosis-Inducing Ligand KW - Tumor Necrosis Factor-alpha KW - Protein Kinases TI - Limiting glutamine utilization activates a GCN2/TRAIL-R2/Caspase-8 apoptotic pathway in glutamine-addicted tumor cells. TY - research article VL - 13 ER -