TY - JOUR AU - Vila-Farres, Xavier AU - Parra-Millan, Raquel AU - Sanchez-Encinales, Viviana AU - Varese, Monica AU - Ayerbe-Algaba, Rafael AU - Bayo, Nuria AU - Guardiola, Salvador AU - Pachon-Ibañez, María Eugenia AU - Kotev, Martin AU - Garcia, Jesus AU - Teixido, Meritxell AU - Vila, Jordi AU - Pachon, Jeronimo AU - Giralt, Ernest AU - Smani, Younes PY - 2017 DO - 10.1038/s41598-017-14972-y UR - http://hdl.handle.net/10668/11756 T2 - Scientific reports AB - Preventing the adhesion of pathogens to host cells provides an innovative approach to tackling multidrug-resistant bacteria. In this regard, the identification of outer membrane protein A (OmpA) as a key bacterial virulence factor has been a major... LA - en PB - Nature Publishing Group KW - Drug discovery and development KW - Pathogens KW - Acinetobacter Infections KW - Acinetobacter baumannii KW - Alveolar Epithelial Cells KW - Animals KW - Anti-Bacterial Agents KW - Bacterial Adhesion KW - Bacterial Outer Membrane Proteins KW - Biofilms KW - Cell Line KW - DNA Helicases KW - Disease Models, Animal KW - Escherichia coli KW - Escherichia coli Infections KW - Female KW - Humans KW - Mice KW - Mice, Inbred C57BL KW - Multifunctional Enzymes KW - Peptides KW - Pseudomonas Infections KW - Pseudomonas aeruginosa KW - RNA Helicases KW - Sepsis KW - Virulence Factors TI - Combating virulence of Gram-negative bacilli by OmpA inhibition. TY - research article VL - 7 ER -