RT Journal Article
T1 Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study.
A1 Escrihuela-Vidal, Francesc
A1 Lopez-Cortes, Luis Eduardo
A1 Escola-Verge, Laura
A1 De-Alarcon-Gonzalez, Aristides
A1 Cuervo, Guillermo
A1 Sanchez-Porto, Antonio
A1 Fernandez-Hidalgo, Nuria
A1 Luque, Rafael
A1 Montejo, Miguel
A1 Miro, Jose M
A1 Goenaga, Miguel Angel
A1 Muñoz, Patricia
A1 Valerio, Maricela
A1 Ripa, Marco
A1 Sousa-Regueiro, Dolores
A1 Gurgui Merce, 
A1 Fariñas-Alvarez, Maria Carmen
A1 Mateu, Lourdes
A1 Garcia Vazquez, Elisa
A1 Galvez-Acebal, Juan
A1 Carratala, Jordi
K1 Streptococcus anginosus
K1 Streptococcus gallolyticus
K1 infective endocarditis
K1 viridans group streptococci
AB Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption. We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis. Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When comparing SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups. SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.
PB Oxford University Press
SN 2328-8957
YR 2021
FD 2021-03-29
LK https://hdl.handle.net/10668/27759
UL https://hdl.handle.net/10668/27759
LA en
NO Escrihuela-Vidal F, López-Cortés LE, Escolà-Vergé L, De Alarcón González A, Cuervo G, Sánchez-Porto A, et al. Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study. Open Forum Infect Dis. 2021 Mar 29;8(6):ofab163.
DS RISalud
RD Apr 17, 2025