%0 Journal Article
%A Escrihuela-Vidal, Francesc
%A Lopez-Cortes, Luis Eduardo
%A Escola-Verge, Laura
%A De-Alarcon-Gonzalez, Aristides
%A Cuervo, Guillermo
%A Sanchez-Porto, Antonio
%A Fernandez-Hidalgo, Nuria
%A Luque, Rafael
%A Montejo, Miguel
%A Miro, Jose M
%A Goenaga, Miguel Angel
%A Muñoz, Patricia
%A Valerio, Maricela
%A Ripa, Marco
%A Sousa-Regueiro, Dolores
%A Gurgui Merce
%A Fariñas-Alvarez, Maria Carmen
%A Mateu, Lourdes
%A Garcia Vazquez, Elisa
%A Galvez-Acebal, Juan
%A Carratala, Jordi
%T Clinical Features and Outcomes of Streptococcus anginosus Group Infective Endocarditis: A Multicenter Matched Cohort Study.
%D 2021
%@ 2328-8957
%U https://hdl.handle.net/10668/27759
%X Although Streptococcus anginosus group (SAG) endocarditis is considered a severe disease associated with abscess formation and embolic events, there is limited evidence to support this assumption. We performed a retrospective analysis of prospectively collected data from consecutive patients with definite SAG endocarditis in 28 centers in Spain and Italy. A comparison between cases due to SAG endocarditis and viridans group streptococci (VGS) or Streptococcus gallolyticus group (SGG) was performed in a 1:2 matched analysis. Of 5336 consecutive cases of definite endocarditis, 72 (1.4%) were due to SAG and matched with 144 cases due to VGS/SGG. SAG endocarditis was community acquired in 64 (88.9%) cases and affected aortic native valve in 29 (40.3%). When comparing SAG and VGS/SGG endocarditis, no significant differences were found in septic shock (8.3% vs 3.5%, P = .116); valve disorder, including perforation (22.2% vs 18.1%, P = .584), pseudoaneurysm (16.7% vs 8.3%, P = .108), or prosthesis dehiscence (1.4% vs 6.3%, P = .170); paravalvular complications, including abscess (25% vs 18.8%, P = .264) and intracardiac fistula (5.6% vs 3.5%, P = .485); heart failure (34.7% vs 38.9%, P = .655); or embolic events (41.7% vs 32.6%, P = .248). Indications for surgery (70.8% vs 70.8%; P = 1) and mortality (13.9% vs 16.7%; P = .741) were similar between groups. SAG endocarditis is an infrequent but serious condition that presents a prognosis similar to that of VGS/SGG.
%K Streptococcus anginosus
%K Streptococcus gallolyticus
%K infective endocarditis
%K viridans group streptococci
%~