RT Journal Article
T1 Long-Term Outcomes in Patients With New-Onset Persistent Left Bundle Branch Block Following TAVR.
A1 Chamandi, Chekrallah
A1 Barbanti, Marco
A1 Munoz-Garcia, Antonio
A1 Latib, Azeem
A1 Nombela-Franco, Luis
A1 Gutiérrez-Ibanez, Enrique
A1 Veiga-Fernandez, Gabriela
A1 Cheema, Asim N
A1 Cruz-Gonzalez, Ignacio
A1 Serra, Vicenç
A1 Tamburino, Corrado
A1 Mangieri, Antonio
A1 Colombo, Antonio
A1 Jiménez-Quevedo, Pilar
A1 Elizaga, Jaime
A1 Lee, Dae-Hyun
A1 Garcia Del Blanco, Bruno
A1 Puri, Rishi
A1 Côté, Mélanie
A1 Philippon, François
A1 Rodés-Cabau, Josep
K1 left bundle branch block
K1 left ventricular ejection fraction
K1 long-term outcomes
K1 pacemaker
K1 transcatheter aortic valve replacement
AB The aim of this study was to determine the impact of new-onset persistent (NOP) left bundle branch block (LBBB) on long-term (>2 year) outcomes after transcatheter aortic valve replacement (TAVR). The impact of NOP-LBBB after TAVR remains controversial and no data exist regarding long-term outcomes. A total of 1,020 consecutive patients without pre-existing LBBB or permanent pacemaker implantation (PPI) undergoing TAVR were included. NOP-LBBB was defined as any new LBBB post-TAVR that persisted at hospital discharge. Follow-up clinical and echocardiographic data were obtained at a median of 3 years (interquartile range: 2 to 5 years) post-TAVR. NOP-LBBB occurred in 212 patients (20.1%) following TAVR. There were no differences between NOP-LBBB and no NOP-LBBB groups, except for a higher use of the self-expandable CoreValve system in the NOP-LBBB group (p  After a median follow-up of 3 years post-TAVR, NOP-LBBB was not associated with a higher mortality or heart failure rehospitalization. However, NOP-LBBB increased the risk of permanent pacemaker implantation and negatively impacted left ventricular function over time. These results should inform future efforts for improving the management of patients with NOP-LBBB post-TAVR.
YR 2019
FD 2019-05-22
LK http://hdl.handle.net/10668/14021
UL http://hdl.handle.net/10668/14021
LA en
DS RISalud
RD Apr 5, 2025