%0 Journal Article
%A Chamandi, Chekrallah
%A Barbanti, Marco
%A Munoz-Garcia, Antonio
%A Latib, Azeem
%A Nombela-Franco, Luis
%A Gutiérrez-Ibanez, Enrique
%A Veiga-Fernandez, Gabriela
%A Cheema, Asim N
%A Cruz-Gonzalez, Ignacio
%A Serra, Vicenç
%A Tamburino, Corrado
%A Mangieri, Antonio
%A Colombo, Antonio
%A Jiménez-Quevedo, Pilar
%A Elizaga, Jaime
%A Lee, Dae-Hyun
%A Garcia Del Blanco, Bruno
%A Puri, Rishi
%A Côté, Mélanie
%A Philippon, François
%A Rodés-Cabau, Josep
%T Long-Term Outcomes in Patients With New-Onset Persistent Left Bundle Branch Block Following TAVR.
%D 2019
%U http://hdl.handle.net/10668/14021
%X The aim of this study was to determine the impact of new-onset persistent (NOP) left bundle branch block (LBBB) on long-term (>2 year) outcomes after transcatheter aortic valve replacement (TAVR). The impact of NOP-LBBB after TAVR remains controversial and no data exist regarding long-term outcomes. A total of 1,020 consecutive patients without pre-existing LBBB or permanent pacemaker implantation (PPI) undergoing TAVR were included. NOP-LBBB was defined as any new LBBB post-TAVR that persisted at hospital discharge. Follow-up clinical and echocardiographic data were obtained at a median of 3 years (interquartile range: 2 to 5 years) post-TAVR. NOP-LBBB occurred in 212 patients (20.1%) following TAVR. There were no differences between NOP-LBBB and no NOP-LBBB groups, except for a higher use of the self-expandable CoreValve system in the NOP-LBBB group (p  After a median follow-up of 3 years post-TAVR, NOP-LBBB was not associated with a higher mortality or heart failure rehospitalization. However, NOP-LBBB increased the risk of permanent pacemaker implantation and negatively impacted left ventricular function over time. These results should inform future efforts for improving the management of patients with NOP-LBBB post-TAVR.
%K left bundle branch block
%K left ventricular ejection fraction
%K long-term outcomes
%K pacemaker
%K transcatheter aortic valve replacement
%~