TY - JOUR AU - Ruiz-Extremera, A AU - Pavón-Castillero, E J AU - Florido, M AU - Muñoz de Rueda, P AU - Muñoz-Gámez, J A AU - Casado, J AU - Carazo, A AU - Quiles, R AU - Jiménez-Ruiz, S M AU - Gila, A AU - Luna, J D AU - León, J AU - Salmerón, J PY - 2017 DO - 10.1371/journal.pone.0172527 UR - http://hdl.handle.net/10668/2589 T2 - PloS One AB - BACKGROUND & AIMThere is evidence that maternal viral load of HCV during delivery influences the risk for Mother-to-child transmission (MTCT), but this does not explain all cases. We study the role of the immunogenetic profile (HLA, KIRs and... LA - en PB - Public Library of Science KW - Alelos KW - Niño KW - Antígenos HLA-B KW - Hepatitis C KW - Humanos KW - Inmunogenética KW - Células asesinas naturales KW - Madres KW - ARN KW - Receptores KIR KW - Linfocitos T KW - Carga viral KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Child KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Histocompatibility Antigens Class I::HLA-B Antigens KW - Medical Subject Headings::Diseases::Virus Diseases::Hepatitis, Viral, Human::Hepatitis C KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Immunogenetics KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::Killer Cells, Natural KW - Medical Subject Headings::Named Groups::Persons::Parents::Mothers KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Natural Killer Cell::Receptors, KIR KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Microbiological Techniques::Viral Load TI - Influence of HLA class I, HLA class II and KIRs on vertical transmission and chronicity of hepatitis C virus in children. TY - research article ER -