TY  - JOUR
AU  - Rodríguez, María Isabel
AU  - Peralta-Leal, Andreína
AU  - O'Valle, Francisco
AU  - Rodriguez-Vargas, José Manuel
AU  - Gonzalez-Flores, Ariannys
AU  - Majuelos-Melguizo, Jara
AU  - López, Laura
AU  - Serrano, Santiago
AU  - García de Herreros, Antonio
AU  - Rodríguez-Manzaneque, Juan Carlos
AU  - Fernández, Rubén
AU  - Moral, Raimundo G Del
AU  - Almodóvar, José Mariano de
AU  - Oliver, F Javier
PY  - 2013
DO  - 10.1371/journal.pgen.1003531
SN  - 1553-7390
UR  - http://hdl.handle.net/10668/1640
T2  - PLoS Genetics
AB  - PARP inhibition can induce anti-neoplastic effects when used as monotherapy or in combination with chemo- or radiotherapy in various tumor settings; however, the basis for the anti-metastasic activities resulting from PARP inhibition remains unknown....
LA  - en
KW  - Antígenos CD
KW  - Neoplasias de la Mama
KW  - Cadherinas
KW  - Línea Celular Tumoral
KW  - Transformación Celular Neoplásica
KW  - Perros
KW  - Células Endoteliales
KW  - Transición Epitelial-Mesenquimal
KW  - Femenino
KW  - Regulación Neoplásica de la Expresión Génica
KW  - Células Endoteliales de la Vena Umbilical Humana
KW  - Humanos
KW  - Células MCF-7
KW  - Ratones
KW  - Melanoma Experimental
KW  - Invasividad Neoplásica
KW  - Metástasis de la Neoplasia
KW  - Poli(ADP-Ribosa) Polimerasas
KW  - Vimentina
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Antigens, Differentiation::Antigens, CD
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Breast Neoplasms
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface::Cell Adhesion Molecules::Cadherins
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Cell Transformation, Neoplastic
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Carnivora::Canidae::Dogs
KW  - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Transdifferentiation::Epithelial-Mesenchymal Transition
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic
KW  - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells::Human Umbilical Vein Endothelial Cells
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms, Experimental::Melanoma, Experimental
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Neoplasm Invasiveness
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Neoplasm Metastasis
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Glycosyltransferases::Pentosyltransferases::ADP Ribose Transferases::Poly(ADP-ribose) Polymerases
KW  - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Intermediate Filament Proteins::Vimentin
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::MCF-7 Cells
TI  - PARP-1 regulates metastatic melanoma through modulation of vimentin-induced malignant transformation.
TY  - research article
ER  -