TY  - JOUR
AU  - Lagarrigue, Sylviane
AU  - Lopez-Mejia, Isabel C
AU  - Denechaud, Pierre-Damien
AU  - Escoté, Xavier
AU  - Castillo-Armengol, Judit
AU  - Jimenez, Veronica
AU  - Chavey, Carine
AU  - Giralt, Albert
AU  - Lai, Qiuwen
AU  - Zhang, Lianjun
AU  - Martinez-Carreres, Laia
AU  - Delacuisine, Brigitte
AU  - Annicotte, Jean-Sébastien
AU  - Blanchet, Emilie
AU  - Huré, Sébastien
AU  - Abella, Anna
AU  - Tinahones, Francisco J
AU  - Vendrell, Joan
AU  - Dubus, Pierre
AU  - Bosch, Fatima
AU  - Kahn, C Ronald
AU  - Fajas, Lluis
PY  - 2015
DO  - 10.1172/JCI81480
UR  - http://hdl.handle.net/10668/9660
T2  - The Journal of clinical investigation
AB  - Insulin resistance is a fundamental pathogenic factor that characterizes various metabolic disorders, including obesity and type 2 diabetes. Adipose tissue contributes to the development of obesity-related insulin resistance through increased release...
LA  - en
KW  - 3T3-L1 Cells
KW  - Adipocytes
KW  - Adipose Tissue, White
KW  - Animals
KW  - Cyclin D3
KW  - Cyclin-Dependent Kinase 4
KW  - E2F1 Transcription Factor
KW  - Female
KW  - Humans
KW  - Insulin
KW  - Insulin Receptor Substrate Proteins
KW  - Insulin Resistance
KW  - Lipid Metabolism
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Phosphorylation
KW  - Signal Transduction
TI  - CDK4 is an essential insulin effector in adipocytes.
TY  - research article
VL  - 126
ER  -