TY - JOUR AU - Duran, I AU - Lambea, J AU - Maroto, P AU - González-Larriba, J L AU - Flores, Luis AU - Granados-Principal, S AU - Graupera, M AU - Sáez, B AU - Vivancos, A AU - Casanovas, O PY - 2017 DO - 10.1007/s11523-016-0463-4 UR - http://hdl.handle.net/10668/10604 T2 - Targeted oncology AB - Renal cell carcinoma (RCC) is a complex disease characterized by mutations in several genes. Loss of function of the von Hippel-Lindau (VHL) tumour suppressor gene is a very common finding in RCC and leads to up-regulation of hypoxia-inducible factor... LA - en KW - Drug Resistance, Neoplasm KW - Humans KW - Kidney Neoplasms TI - Resistance to Targeted Therapies in Renal Cancer: The Importance of Changing the Mechanism of Action. TY - research article VL - 12 ER -