TY  - JOUR
AU  - Chachlaki, Konstantina
AU  - Messina, Andrea
AU  - Delli, Virginia
AU  - Leysen, Valerie
AU  - Maurnyi, Csilla
AU  - Huber, Chieko
AU  - Ternier, Gaëtan
AU  - Skrapits, Katalin
AU  - Papadakis, Georgios
AU  - Shruti, Sonal
AU  - Kapanidou, Maria
AU  - Cheng, Xu
AU  - Acierno, James
AU  - Rademaker, Jesse
AU  - Rasika, Sowmyalakshmi
AU  - Quinton, Richard
AU  - Niedziela, Marek
AU  - L'Allemand, Dagmar
AU  - Pignatelli, Duarte
AU  - Dirlewander, Mirjam
AU  - Lang-Muritano, Mariarosaria
AU  - Kempf, Patrick
AU  - Catteau-Jonard, Sophie
AU  - Niederländer, Nicolas J
AU  - Ciofi, Philippe
AU  - Tena-Sempere, Manuel
AU  - Garthwaite, John
AU  - Storme, Laurent
AU  - Avan, Paul
AU  - Hrabovszky, Erik
AU  - Carleton, Alan
AU  - Santoni, Federico
AU  - Giacobini, Paolo
AU  - Pitteloud, Nelly
AU  - Prevot, Vincent
PY  - 2022
DO  - 10.1126/scitranslmed.abh2369
UR  - http://hdl.handle.net/10668/20031
T2  - Science translational medicine
AB  - The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for reproduction. We hypothesized that a disruption of neuronal NO synthase...
LA  - en
PB  - American Association for the Advancement of Science (AAAS)
KW  - Mutant Proteins
KW  - Mutation
KW  - Nitric Oxide
KW  - Nitric Oxide Synthase Type I
KW  - Nitrites
KW  - Animals
KW  - Cognition
KW  - Gonadotropin-Releasing Hormone
KW  - Humans
KW  - Hypogonadism
KW  - Mice
TI  - NOS1 mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice.
TY  - research article
VL  - 14
ER  -