TY  - JOUR
AU  - Xu, Jimin
AU  - Berastegui-Cabrera, Judith
AU  - Carretero-Ledesma, Marta
AU  - Chen, Haiying
AU  - Xue, Yu
AU  - Wold, Eric A.
AU  - Pachón, Jerónimo
AU  - Zhou, Jia
AU  - Sánchez-Céspedes, Javier
PY  - 2021
DO  - 10.3390/ijms22041617
UR  - http://hdl.handle.net/10668/3893
T2  - International Journal of Molecular Sciences
AB  - Human adenoviruses (HAdVs) display a wide range of tissue tropism and can cause an array of symptoms from mild respiratory illnesses to disseminated and life-threatening infections in immunocompromised individuals. However, no antiviral drug has been...
LA  - en
PB  - MDPI
KW  - Antiviral agent
KW  - Adenovirus
KW  - Salicylamide derivatives
KW  - Entry inhibition
KW  - Antivíricos
KW  - Adenoviridae
KW  - Endosomas
KW  - Infecciones
KW  - Virus
KW  - Niclosamida
KW  - Medical Subject Headings::Organisms::Viruses::DNA Viruses::Adenoviridae::Mastadenovirus::Adenoviruses, Human
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Transport Vesicles::Endosomes
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Transformed::HEK293 Cells
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Toxicity Tests::Inhibitory Concentration 50
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Anilides::Salicylanilides::Niclosamide
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Salicylamides
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Specialty Uses of Chemicals::Laboratory Chemicals::Small Molecule Libraries
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Microbiological Processes::Virus Physiological Processes::Viral Tropism
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Virus Physiological Phenomena::Virus Physiological Processes::Virus Internalization
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Microbiological Processes::Virus Physiological Processes::Virus Replication
TI  - Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome
TY  - research article
ER  -