TY  - JOUR
AU  - Alonso-de Vega, Ignacio
AU  - Paz-Cabrera, Maria Cristina
AU  - Rother, Magdalena B.
AU  - Wiegant, Wouter W.
AU  - Checa-Rodríguez, Cintia
AU  - Hernández-Fernaud, Juan Ramón
AU  - Huertas, Pablo
AU  - Freire, Raimundo
AU  - van Attikum, Haico
AU  - Smits, Veronique A J.
PY  - 2020
DO  - 10.1093/nar/gkaa196
SN  - 0305-1048
UR  - http://hdl.handle.net/10668/3882
T2  - Nucleic Acids Research
AB  - Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the genome. Here, we identify histone lysine demethylase PHF2 as a novel regulator of the DNA damage response by regulating DNA...
LA  - en
PB  - Oxford University Press on behalf of Nucleic Acids Research
KW  - DNA
KW  - BRCA1 Protein
KW  - DNA damage
KW  - DNA repair
KW  - Histone
KW  - Phosphorylation
KW  - ADN
KW  - Proteína BRCA1
KW  - Daño del ADN
KW  - Reparación del ADN
KW  - Histonas
KW  - Fosforilación
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nuclear Proteins::BRCA1 Protein
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Endonucleases::Endodeoxyribonucleases
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genomic Instability
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::HeLa Cells
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-NH Group Donors::Oxidoreductases, N-Demethylating::Histone Demethylases
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Homeodomain Proteins
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::Recombinational DNA Repair
TI  - PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks
TY  - research article
ER  -