TY - JOUR AU - Pavillard, Luis E. AU - Canadas-Lozano, Diego AU - Alcocer-Gomez, Elisabet AU - Marin-Aguilar, Fabiola AU - Pereira, Sheila AU - Robertson, Avril A. B. AU - Muntane, Jordi AU - Ryffel, Bernhard AU - Cooper, Matthew A. AU - Quiles, Jose L. AU - Bullon, Pedro AU - Ruiz-Cabello, Jesus AU - Cordero, Mario D. PY - 2017 DO - 10.18632/oncotarget.20763 UR - http://hdl.handle.net/10668/19443 T2 - Oncotarget AB - The NLRP3-inflammasome complex has emerged as an important component of inflammatory processes in metabolic dysfunction induced by high-caloric diets. In this study, we investigate the molecular mechanisms by which NLRP3 inhibition may attenuate... LA - en PB - Impact journals llc KW - NLRP3-inflammasome KW - cardiac damage KW - autophagy KW - MCC950 KW - Nlrp3 inflammasome activation KW - Low-grade inflammation KW - Adipose-tissue KW - Obesity KW - Health KW - Mice KW - Fibrosis KW - Disease KW - Stress KW - Injury TI - NLRP3-inflammasome inhibition prevents high fat and high sugar diets-induced heart damage through autophagy induction TY - research article VL - 8 ER -