TY  - JOUR
AU  - Oliva-Martin, Maria Jose
AU  - Sanchez-Abarca, Luis Ignacio
AU  - Rodhe, Johanna
AU  - Carrillo-Jimenez, Alejandro
AU  - Vlachos, Pinelopi
AU  - Herrera, Antonio Jose
AU  - Garcia-Quintanilla, Albert
AU  - Caballero-Velazquez, Teresa
AU  - Perez-Simon, Jose Antonio
AU  - Joseph, Bertrand
AU  - Venero, Jose Luis
PY  - 2016
DO  - 10.18632/oncotarget.9648
UR  - http://hdl.handle.net/10668/10141
T2  - Oncotarget
AB  - In septic patients, the onset of septic shock occurs due to the over-activation of monocytes. We tested the therapeutic potential of directly targeting innate immune cell activation to limit the cytokine storm and downstream phases. We initially...
LA  - en
PB  - Impact Journals LLC
KW  - Pathology Section
KW  - caspase-8
KW  - inflammation
KW  - monocyte
KW  - necroptosis
KW  - sepsis
KW  - Animals
KW  - Caspase 8
KW  - Caspase Inhibitors
KW  - Cells, Cultured
KW  - Cytokines
KW  - Disease Models, Animal
KW  - Humans
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Monocytes
KW  - Shock, Septic
TI  - Caspase-8 inhibition represses initial human monocyte activation in septic shock model.
TY  - research article
VL  - 7
ER  -