TY - JOUR AU - Pulido, MarĂ­a AU - Chamorro, Virginia AU - Romero, Irene AU - Algarra, Ignacio AU - S-Montalvo, Alba AU - Collado, Antonia AU - Garrido, Federico AU - Garcia-Lora, Angel M PY - 2020 DO - 10.3390/cancers12061563 SN - 2072-6694 UR - https://hdl.handle.net/10668/28185 T2 - Cancers AB - The capacity of cytotoxic-T lymphocytes to recognize and destroy tumor cells depends on the surface expression by tumor cells of MHC class I molecules loaded with tumor antigen peptides. Loss of MHC-I expression is the most frequent mechanism by which... LA - en KW - Fhit KW - MHC-I restoration KW - antitumor immunity KW - cytotoxic T lymphocytes KW - immune profile KW - immunotherapy KW - vaccine TI - Restoration of MHC-I on Tumor Cells by Fhit Transfection Promotes Immune Rejection and Acts as an Individualized Immunotherapeutic Vaccine. TY - research article VL - 12 ER -