%0 Generic
%A Vega-García, N
%A Torrebadell, M
%A Jiménez-Velasco, A
%A Ortega, M
%A Abad, L
%A Pratcorona, M
%A Muñoz, L
%A Malatesta, R
%A Calvente, L
%A Català, A
%A Berrueco, R
%A Ruiz-Llobet, A
%A Estella, C
%A Trabazo, M
%A Alonso-Saladrigues, A
%A Mesegué, M
%A Pascual, A
%A Lassaletta, Á
%A Badell, I
%A Pisa, S
%A Velasco, MR
%A Dapena, JL
%A Rives, S
%A Ramirez-Orellana, M
%A Camós, M
%T Risk factors in pediatric T-cell acute lymphoblastic leukemia: a collaborative study of the biological committee of the leukemia group of the Spanish Hematology and Oncology Pediatric Society
%D 2016
%@ 0390-6078
%U http://hdl.handle.net/10668/2435
%X Background: Useful biomarkers for risk stratification in pediatric T-ALL arestill needed. Several biological variables have been proposed as new prognosticbiomarkers, including NOTCH1, FBXW7, PTEN & RAS mutations,expression of myeloid antigens and presence of copy number alterations(CNAs) of certain genes, but published results are controversial.Aims: To analyze the prognostic impact of mutations, CNAs and myeloid antigensexpression in a series of 56 pediatric T-ALL patients.
%K Biomarcadores
%K Proteínas del ciclo celular
%K Niño
%K Proteínas F-box
%K Humanos
%K Mutación
%K Leucemia-linfoma linfoblástico de células T precursoras
%K Ubicuitina-proteína ligasas
%~