RT Journal Article
T1 Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman.
A1 Molina-Mesa, Soledad
A1 Martinez-Cendan, Juan Pedro
A1 Moyano-Rubiales, Daniel
A1 Cubillas-Rodriguez, Inmaculada
A1 Molina-Garcia, Jorge
A1 Gonzalez-Mesa, Ernesto
K1 Arsenic
K1 Cadmium
K1 Contaminants
K1 Dietary habits
K1 Heavy metals
K1 Lead
K1 Mercury
K1 Placenta
K1 Pregnancy
K1 Toxicity
AB Heavy metals can cross the placental barrier and reach the fetal compartment, threatening fetal development. Pregnant women can acquire these through food, drinking water, toxic habits or simply by breathing polluted air. The placenta has been described as a biomarker of maternal and fetal exposure to different toxic elements. The main objective of this study was to test the possible existence of heavy metal deposits (Pb, As, Cd and Hg) in the placentas of women who gave birth at term in our setting, analyzing the influence of daily life and dietary habits. We studied 103 placentas, obtained by consecutive sampling, of women that delivered in the Regional Maternity Hospital of Malaga between March and June, 2021. As, Cd and Pb concentrations were analyzed using mass spectrometry techniques. Hg concentration was studied according to US EPA method 7473. Women also answered a questionnaire with epidemiological variables. Detectable concentrations were found in 14.56% [As], 44.6% [Cd], 81.5% [Pb] and 100% [Hg]. [Pb] and [As] correlated significantly (Spearman's Rho of 0.91 and <0.001), as did [Hg] and [Cd] (Spearman’s Rho 0.256, p < 0.004). The [Pb] and [AS] concentrations were significantly higher in cases of tap water consumption. [Hg] concentrations predicted the birth weight of female newborns.
PB MDPI
YR 2022
FD 2022-11-09
LK http://hdl.handle.net/10668/21120
UL http://hdl.handle.net/10668/21120
LA en
NO Molina-Mesa S, Martínez-Cendán JP, Moyano-Rubiales D, Cubillas-Rodríguez I, Molina-García J, González-Mesa E. Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman. Int J Environ Res Public Health. 2022 Nov 9;19(22):14731
DS RISalud
RD Apr 4, 2025