RT Journal Article
T1 Altered adaptive but not veridical decision-making in substance dependent individuals.
A1 Verdejo-García, Antonio
A1 Vilar-López, Raquel
A1 Pérez-García, Miguel
A1 Podell, Kenneth
A1 Goldberg, Elkhonon
K1 Prefrontal cortex
K1 Addictive behavior
K1 Decision-making
K1 Gambling task
K1 Cognitive bias task
K1 Neuropsychological tests
K1 Adolescente
K1 Adulto
K1 Enfermedad Crónica
K1 Cognición
K1 Toma de Decisiones
K1 Femenino
K1 Juego de Azar
K1 Humanos
K1 Masculino
K1 Mediana Edad
K1 Pruebas Neuropsicológicas
K1 Escalas de Valoración Psiquiátrica
K1 Caracteres Sexuales
K1 Trastornos Relacionados con Sustancias
K1 Adaptación Psicológica
AB Drug addiction is associated with impaired judgment in unstructured situations in which success depends on self-regulation of behavior according to internal goals (adaptive decision-making). However most executive measures are aimed at assessing decision-making in structured scenarios, in which success is determined by external criteria inherent to the situation (veridical decision-making). The aim of this study was to examine the performance of Substance Abusers (SA, n = 97) and Healthy Comparison participants (HC, n = 81) in two behavioral tasks that mimic the uncertainty inherent in real-life decision-making: the Cognitive Bias Task (CB) and the Iowa Gambling Task (IGT) (administered only to SA). A related goal was to study the interdependence between performances on both tasks. We conducted univariate analyses of variance (ANOVAs) to contrast the decision-making performance of both groups; and used correlation analyses to study the relationship between both tasks. SA showed a marked context-independent decision-making strategy on the CB's adaptive condition, but no differences were found on the veridical conditions in a subsample of SA (n = 34) and HC (n = 22). A high percentage of SA (75%) also showed impaired performance on the IGT. Both tasks were only correlated when no impaired participants were selected. Results indicate that SA show abnormal decision-making performance in unstructured situations, but not in veridical situations.
PB Cambridge University Press
SN 1355-6177
YR 2006
FD 2006-01
LK http://hdl.handle.net/10668/701
UL http://hdl.handle.net/10668/701
LA en
NO Verdejo-García A, Vilar-López R, Pérez-García M, Podell K, Goldberg E. Altered adaptive but not veridical decision-making in substance dependent individuals. J Int Neuropsychol Soc. 2006                         ; 12(1):90-9
NO Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 13, 2025