RT Journal Article
T1 Clinical profile and predictors of in-hospital mortality among older patients hospitalised for COVID-19.
A1 Becerra-Muñoz, Víctor Manuel
A1 Núñez-Gil, Iván J
A1 Eid, Charbel Maroun
A1 García Aguado, Marcos
A1 Romero, Rodolfo
A1 Huang, Jia
A1 Mulet, Alba
A1 Ugo, Fabrizio
A1 Rametta, Francesco
A1 Liebetrau, Christoph
A1 Aparisi, Alvaro
A1 Fernández-Rozas, Inmaculada
A1 Viana-Llamas, María C
A1 Feltes, Gisela
A1 Pepe, Martino
A1 Moreno-Rondón, Luis A
A1 Cerrato, Enrico
A1 Raposeiras-Roubín, Sergio
A1 Alfonso, Emilio
A1 Carrero-Fernández, Ana
A1 Buzón-Martín, Luis
A1 Abumayyaleh, Mohammad
A1 Gonzalez, Adelina
A1 Fernández Ortiz, Antonio
A1 Macaya, Carlos
A1 Estrada, Vicente
A1 Fernández-Pérez, Cristina
A1 Gómez-Doblas, Juan José
K1 Coronavirus disease 2019
K1 SARS-CoV-2
K1 comorbidities
K1 older adults
AB the coronavirus disease 2019 (COVID-19) is characterized by poor outcomes and mortality, particularly in older patients. post hoc analysis of the international, multicentre, 'real-world' HOPE COVID-19 registry. All patients aged ≥65 years hospitalised for COVID-19 were selected. Epidemiological, clinical, analytical and outcome data were obtained. A comparative study between two age subgroups, 65-74 and ≥75 years, was performed. The primary endpoint was all cause in-hospital mortality. about, 1,520 patients aged ≥65 years (60.3% male, median age of 76 [IQR 71-83] years) were included. Comorbidities such as hypertension (69.2%), dyslipidaemia (48.6%), cardiovascular diseases (any chronic heart disease in 38.4% and cerebrovascular disease in 12.5%), and chronic lung disease (25.3%) were prevalent, and 49.6% were on ACEI/ARBs. Patients aged 75 years and older suffered more in-hospital complications (respiratory failure, heart failure, renal failure, sepsis) and a significantly higher mortality (18.4 vs. 48.2%, P 1 (OR 8.31) to be independent predictors of mortality. patients aged ≥65 years hospitalised for COVID-19 had high rates of in-hospital complications and mortality, especially among patients 75 years or older. Age ≥75 years, dementia, peripheral oxygen saturation 1 were independent predictors of mortality in this population.
YR 2021
FD 2021
LK http://hdl.handle.net/10668/16618
UL http://hdl.handle.net/10668/16618
LA en
DS RISalud
RD Apr 6, 2025