%0 Journal Article
%A Becerra-Muñoz, Víctor Manuel
%A Núñez-Gil, Iván J
%A Eid, Charbel Maroun
%A García Aguado, Marcos
%A Romero, Rodolfo
%A Huang, Jia
%A Mulet, Alba
%A Ugo, Fabrizio
%A Rametta, Francesco
%A Liebetrau, Christoph
%A Aparisi, Alvaro
%A Fernández-Rozas, Inmaculada
%A Viana-Llamas, María C
%A Feltes, Gisela
%A Pepe, Martino
%A Moreno-Rondón, Luis A
%A Cerrato, Enrico
%A Raposeiras-Roubín, Sergio
%A Alfonso, Emilio
%A Carrero-Fernández, Ana
%A Buzón-Martín, Luis
%A Abumayyaleh, Mohammad
%A Gonzalez, Adelina
%A Fernández Ortiz, Antonio
%A Macaya, Carlos
%A Estrada, Vicente
%A Fernández-Pérez, Cristina
%A Gómez-Doblas, Juan José
%T Clinical profile and predictors of in-hospital mortality among older patients hospitalised for COVID-19.
%D 2021
%U http://hdl.handle.net/10668/16618
%X the coronavirus disease 2019 (COVID-19) is characterized by poor outcomes and mortality, particularly in older patients. post hoc analysis of the international, multicentre, 'real-world' HOPE COVID-19 registry. All patients aged ≥65 years hospitalised for COVID-19 were selected. Epidemiological, clinical, analytical and outcome data were obtained. A comparative study between two age subgroups, 65-74 and ≥75 years, was performed. The primary endpoint was all cause in-hospital mortality. about, 1,520 patients aged ≥65 years (60.3% male, median age of 76 [IQR 71-83] years) were included. Comorbidities such as hypertension (69.2%), dyslipidaemia (48.6%), cardiovascular diseases (any chronic heart disease in 38.4% and cerebrovascular disease in 12.5%), and chronic lung disease (25.3%) were prevalent, and 49.6% were on ACEI/ARBs. Patients aged 75 years and older suffered more in-hospital complications (respiratory failure, heart failure, renal failure, sepsis) and a significantly higher mortality (18.4 vs. 48.2%, P 1 (OR 8.31) to be independent predictors of mortality. patients aged ≥65 years hospitalised for COVID-19 had high rates of in-hospital complications and mortality, especially among patients 75 years or older. Age ≥75 years, dementia, peripheral oxygen saturation 1 were independent predictors of mortality in this population.
%K Coronavirus disease 2019
%K SARS-CoV-2
%K comorbidities
%K older adults
%~