TY - JOUR AU - Zöllner, Stefan K AU - Amatruda, James F AU - Bauer, Sebastian AU - Collaud, Stéphane AU - de Álava, Enrique AU - DuBois, Steven G AU - Hardes, Jendrik AU - Hartmann, Wolfgang AU - Kovar, Heinrich AU - Metzler, Markus AU - Shulman, David S AU - Streitbürger, Arne AU - Timmermann, Beate AU - Toretsky, Jeffrey A AU - Uhlenbruch, Yasmin AU - Vieth, Volker AU - Grünewald, Thomas G P AU - Dirksen, Uta PY - 2021 DO - 10.3390/jcm10081685 SN - 2077-0383 UR - http://hdl.handle.net/10668/17682 T2 - Journal of clinical medicine AB - Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime example of the paradigms of a translocation-positive sarcoma: a genetically rather simple disease with a specific and neomorphic-potential therapeutic target, whose... LA - en KW - EWSR1-FLI1 KW - chromosomal translocation KW - ewing sarcoma KW - fusion protein KW - limb salvage KW - metastasis KW - small round cell sarcoma KW - splicing KW - transcription TI - Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives. TY - research article VL - 10 ER -