RT Journal Article
T1 Cluster Subanalysis of Patients With Severe Asthma Who Responded to Omalizumab.
A1 Davila, I
A1 Campo, P
A1 Cimbollek, S
A1 Almonacid-Sanchez, C
A1 Quirce, S
A1 Moreira, A
A1 Ramirez, A
A1 Soto-Campos, G
K1 Allergens and epitopes
K1 Asthma
K1 Eosinophils
K1 IgE
AB Asthma is a heterogeneous disease that manifests with variations in signs and symptoms, age of onset, triggers, disease progression, pulmonary function, and airway inflammation [1]. Recently, significant efforts have been made to phenotype asthma, with the objective of identifying patients who are responsive to specific therapies [2]. The different methods used to phenotype asthma have generated bias [3]. In this sense, cluster approaches are one of the most frequently used unbiased techniques [4]. They are generally based on cohorts of patients analyzed using a cluster methodology, which gives rise to various phenotypes [5-7]. Here, we used an innovative contrasting approach, namely, a real-world study in which we selected patients with an excellent response to omalizumab (hyperresponders) and performed a cluster analysis to identify responder phenotypes.
PB Esmon Publicidad
SN 1018-9068
YR 2021
FD 2021-07-05
LK http://hdl.handle.net/10668/21740
UL http://hdl.handle.net/10668/21740
LA en
NO Dávila I, Campo P, Cimbollek S, Almonacid Sánchez C, Quirce S, Moreira A, et al. Cluster Subanalysis of Patients With Severe Asthma Who Responded to Omalizumab. J Investig Allergol Clin Immunol. 2022 Jun 20;32(3):213-215
DS RISalud
RD Apr 14, 2025