TY  - JOUR
AU  - García-Heredia, José M
AU  - Verdugo Sivianes, Eva M
AU  - Lucena-Cacace, Antonio
AU  - Molina-Pinelo, Sonia
AU  - Carnero, Amancio
PY  - 2016
DO  - 10.18632/oncotarget.11553
UR  - http://hdl.handle.net/10668/10430
T2  - Oncotarget
AB  - NumbL, or Numb-like, is a close homologue of Numb, and is part of an evolutionary conserved protein family implicated in some important cellular processes. Numb is a protein involved in cell development, in cell adhesion and migration, in asymmetric...
LA  - en
KW  - Notch
KW  - NumbL
KW  - cancer stem cells
KW  - tumor suppressor
KW  - tumorigenicity
KW  - Active Transport, Cell Nucleus
KW  - Animals
KW  - Antineoplastic Agents
KW  - Breast Neoplasms
KW  - Carcinogenesis
KW  - Cell Adhesion
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Colorectal Neoplasms
KW  - Dose-Response Relationship, Drug
KW  - Down-Regulation
KW  - Drug Resistance, Neoplasm
KW  - Endocytosis
KW  - Epithelial-Mesenchymal Transition
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - HeLa Cells
KW  - Humans
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lung Neoplasms
KW  - Mice
KW  - Neoplastic Stem Cells
KW  - Receptors, Notch
KW  - Sarcoma
TI  - Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy.
TY  - research article
VL  - 7
ER  -