RT Journal Article T1 Assessment of the Phytochemical and Nutrimental Composition of Dark Chia Seed (Salvia hispanica L.) A1 Rodriguez Lara, Avilene A1 Mesa-Garcia, Maria Dolores A1 Medina, Karla Alejandra Damian A1 Quirantes Pine, Rosa A1 Casuso, Rafael A. A1 Segura Carretero, Antonio A1 Huertas, Jesus Rodriguez K1 chia seed K1 functional food K1 fiber K1 omega-3 K1 polyunsaturated fatty acids K1 essential amino acids K1 nucleosides K1 phenolic compounds K1 Tandem mass-spectrometry K1 Fatty-acid-composition K1 Antioxidant activity K1 Phenolic-compounds K1 Metabolomic analysis K1 Dietary-fiber K1 Amino-acids K1 In-vitro K1 Performance K1 Quality AB Chia seeds are rich sources of different macro and micronutrients associated with health benefits; thus, they may be considered as a functional food. However, the composition depends on the variety, origin, climate and soil. Here, we show a comprehensive characterization of extractable and non-extractable phenolic compounds of dark chia seed Salvia hispanica L. using high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight (HPLC-ESI-QTOF) and discuss potential health benefits associated with the presence of a number of nutritional and bioactive compounds. We report that dark chia from Jalisco is a high-fiber food, containing omega-3 polyunsaturated fatty acids, essential amino acids (phenylalanine and tryptophan), and nucleosides (adenosine, guanidine and uridine), and rich in antioxidant phenolic compounds, mainly caffeic acid metabolites. Our data suggest that chia seeds may be used as ingredients for the development of functional foods and dietary supplements. PB Mdpi YR 2021 FD 2021-12-01 LK https://hdl.handle.net/10668/28042 UL https://hdl.handle.net/10668/28042 LA en DS RISalud RD Apr 12, 2025