RT Journal Article T1 The Assessment of Myocardial Longitudinal Strain in a Paediatric Spanish Population Using a New Software Analysis. A1 Aristizabal-Duque, Cristhian H A1 Fernandez Cabeza, Juan A1 Blancas Sanchez, Isabel Maria A1 Delgado Ortega, Monica A1 Aparicio Martinez, Pilar A1 Romero-Saldaña, Manuel A1 Fonseca Del Pozo, Francisco Javier A1 Pan, Manuel A1 Ruiz Ortiz, Martin A1 Mesa-Rubio, Maria Dolores K1 Ehocardiography K1 Child K1 Myocardial strain K1 Speckle-tracking K1 Ventricular function AB Two-dimensional speckle-tracking echocardiography (2DSTE) has been present for years. However, it is underutilized due to the expertise and time requirements for its analysis. Our aims were to provide strain values in a paediatric Spanish population and to assess the feasibility and reproducibility of a new strain software analysis in our environment. A cross-sectional study of 156 healthy children aged 6 to 17 years. Longitudinal strain (LS) analysis of the left ventricle, right ventricle, and left atrium was performed. Feasibility and reproducibility were assessed. The associations of clinical and echocardiographic variables with strain values were investigated by multivariate analysis. Mean age was 11 ± 3 years (50% female). Feasibility of LS measurement ranged from 94.2% for left ventricle global LS (LVGLS) to 98.1% for other chamber strain parameters. Strain values were 26.7 ± 2.3% for LVGLS; 30.5 ± 4.4% and 26.9 ± 4% for right ventricle free wall LS (RVFWLS) and four chambers view LS (RV4CLS) respectively; and 57.8 ± 10.5%, 44.9 ± 9.5%, and 12.9 ± 5.5% for left atrium LS reservoir phase (LALSr), conduct phase (LALScd) and contraction phase (LALSct), also respectively. Body surface area (BSA) and age presented a negative correlation with strain values. Higher values were found in females than in males, except for LALScd. Excellent intra- and inter-observer reproducibility were found for right and left ventricular strain measurement, with intraclass correlation coefficients (ICC) ranging from 0.88 to 0.98, respectively. In conclusion, we described strain values in a healthy Spanish paediatric population. LS assessment by this new strain analysis software by semi-automatic manner was highly feasible and reproducible. PB MDPI SN 2077-0383 YR 2022 FD 2022-06-03 LK http://hdl.handle.net/10668/21294 UL http://hdl.handle.net/10668/21294 LA en NO Aristizábal-Duque CH, Fernández Cabeza J, Blancas Sánchez IM, Delgado Ortega M, Aparicio Martinez P, Romero-Saldaña M, et al. The Assessment of Myocardial Longitudinal Strain in a Paediatric Spanish Population Using a New Software Analysis. J Clin Med. 2022 Jun 8;11(12):3272 DS RISalud RD Apr 18, 2025