TY - JOUR AU - Feng, Weijun AU - Kawauchi, Daisuke AU - Körkel-Qu, Huiqin AU - Deng, Huan AU - Serger, Elisabeth AU - Sieber, Laura AU - Lieberman, Jenna Ariel AU - Jimeno-González, Silvia AU - Lambo, Sander AU - Hanna, Bola S AU - Harim, Yassin AU - Jansen, Malin AU - Neuerburg, Anna AU - Friesen, Olga AU - Zuckermann, Marc AU - Rajendran, Vijayanad AU - Gronych, Jan AU - Ayrault, Olivier AU - Korshunov, Andrey AU - Jones, David T W AU - Kool, Marcel AU - Northcott, Paul A AU - Lichter, Peter AU - Cortés-Ledesma, Felipe AU - Pfister, Stefan M AU - Liu, Hai-Kun PY - 2017 DO - 10.1038/ncomms14758 UR - http://hdl.handle.net/10668/10974 T2 - Nature communications AB - Mutations in chromatin modifier genes are frequently associated with neurodevelopmental diseases. We herein demonstrate that the chromodomain helicase DNA-binding protein 7 (Chd7), frequently associated with CHARGE syndrome, is indispensable for... LA - en KW - Animals KW - Brain KW - Cell Differentiation KW - Cerebellum KW - Chromatin KW - DNA-Binding Proteins KW - Gene Expression Profiling KW - Gene Expression Regulation, Developmental KW - Humans KW - Mammals KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Neurons TI - Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. TY - research article VL - 8 ER -