TY - JOUR AU - Crovace, Alberto Maria AU - Lacitignola, Luca AU - Forleo, Donato Monopoli AU - Staffieri, Francesco AU - Francioso, Edda AU - Di Meo, Antonio AU - Becerra, José AU - Crovace, Antonio AU - Santos-Ruiz, Leonor PY - 2020 DO - 10.3390/ani10081389 UR - http://hdl.handle.net/10668/4539 T2 - Animals AB - The main goal in the treatment of large bone defects is to guarantee a rapid loading of the affected limb. In this paper, the authors proposed a new reconstructive technique that proved to be suitable to reach this purpose through the use of a... LA - en PB - MDPI KW - Bone KW - Bone fracture KW - Bone repair KW - Metal endo-implant KW - Titanium alloy KW - Additive manufacturing KW - EBM (electron beam melting) KW - Biomechanics KW - Critical-size bone defect KW - Sheep KW - Animal model KW - Osseointegration KW - Huesos KW - Fracturas óseas KW - Titanio KW - Biomecánica KW - Ovinos KW - Modelos animales KW - Oseointegración KW - Prótesis e implantes KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Sheep KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Metals::Alloys KW - Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Bone Remodeling::Bone Regeneration::Osseointegration KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Porosity KW - Medical Subject Headings::Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Diaphyses KW - Medical Subject Headings::Anatomy::Musculoskeletal System::Skeleton::Bone and Bones::Bones of Lower Extremity::Leg Bones::Tibia KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Acids::Acids, Noncarboxylic::Phosphorus Acids::Phosphoric Acids::Phosphates::Calcium Phosphates::Apatites::Hydroxyapatites::Durapatite KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biotechnology::Biomimetics KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::X-Rays KW - Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Elementary Particles::Electrons KW - Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Motivation::Goals KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight KW - Medical Subject Headings::Diseases::Wounds and Injuries::Fractures, Bone KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Prostheses and Implants TI - 3D Biomimetic Porous Titanium (Ti6Al4V ELI) Scaffolds for Large Bone Critical Defect Reconstruction: An Experimental Study in Sheep TY - research article ER -