RT Journal Article
T1 Quality of life improvement in patients with bone metastases undergoing palliative radiotherapy.
A1 Cañón, Verónica
A1 Gómez-Iturriaga, Alfonso
A1 Casquero, Francisco
A1 Rades, Dirk
A1 Navarro, Arturo
A1 Del Hoyo, Olga
A1 Morillo, Virginia
A1 Willisch, Patricia
A1 López-Guerra, José Luis
A1 Illescas-Vacas, Ana
A1 Ciervide, Raquel
A1 Martinez-Indart, Lorea
A1 Cacicedo, Jon
K1 bone metastases
K1 pain
K1 palliative radiotherapy
K1 quality of life
AB The aim of the study was to analyze the impact of palliative radiotherapy on quality of life (QoL) in patients with symptomatic bone metastases. We present the results from a prospective multicentric study including 128 patients who provided pre- and post-radiotherapy (one month after treatment) brief pain inventory (BPI) assessments. Worst pain was recorded using the BPI (range: 0-10). Pain response was described according to the International Bone Metastases Consensus on palliative radiation. Regarding QoL, for each pre- and post-radiation BPI-questionnaire, scores from the interference domains were summed and averaged to obtain an overall interference score. There was a significant correlation between radiation treatment response and improvement in all functional interference domains except sleeping. Patients > 75 years old presented a significantly higher improvement in general activity, mood and relationships with others compared to patients ≤ 75 years old. Patients presenting a baseline pain score ≥ 8 showed a higher improvement in the general activity item (p = 0.049). There was no statistically significant association between pretreatment ECOG, chemotherapy, primary tumor location and radiation schedule with any of the functional interference items. Patients who report pain relief after palliative radiotherapy also present a better quality of life including physical and psychosocial aspects.
SN 1507-1367
YR 2022
FD 2022-07-29
LK http://hdl.handle.net/10668/21664
UL http://hdl.handle.net/10668/21664
LA en
DS RISalud
RD Jul 30, 2025