TY  - JOUR
AU  - Romero-Zerbo, Silvana Y
AU  - Ruz-Maldonado, Inmaculada
AU  - Espinosa-Jiménez, Vanesa
AU  - Rafacho, Alex
AU  - Gómez-Conde, Ana I
AU  - Sánchez-Salido, Lourdes
AU  - Cobo-Vuilleumier, Nadia
AU  - Gauthier, Benoit R
AU  - Tinahones, Francisco J
AU  - Persaud, Shanta J
AU  - Bermúdez-Silva, Francisco J
PY  - 2017
DO  - 10.1038/s41598-017-03292-w
UR  - http://hdl.handle.net/10668/11331
T2  - Scientific reports
AB  - LH-21 is a triazol derivative that has been described as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear. It has been associated with anti-obesity actions in obese rats. However, its role in preventing type 2 diabetes...
LA  - en
KW  - Animals
KW  - Anxiety
KW  - Behavior, Animal
KW  - Blood Glucose
KW  - Diet, High-Fat
KW  - Disease Models, Animal
KW  - Inflammation Mediators
KW  - Insulin
KW  - Islets of Langerhans
KW  - Liver
KW  - Mice, Inbred C57BL
KW  - Obesity
KW  - Prediabetic State
KW  - Receptor, Cannabinoid, CB1
KW  - Triazoles
TI  - The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice.
TY  - research article
VL  - 7
ER  -