RT Journal Article
T1 Impact of Recommended Maternal Vaccination Programs on the Clinical Presentation of SARS-CoV-2 Infection: A Prospective Observational Study.
A1 de la Cruz Conty, Maria Luisa
A1 Encinas Pardilla, Maria Begoña
A1 Garcia Sanchez, Marta
A1 Gonzalez Rodriguez, Laura
A1 Muner-Hernando, Marta Luisa
A1 Royuela Vicente, Ana
A1 Pintado Recarte, Pilar
A1 Martinez Varea, Alicia
A1 Martinez Diago, Clara
A1 Cruz Melguizo, Sara
A1 Martinez-Perez, Oscar
A1 On Behalf Of The Spanish Obstetric Emergency Group, 
K1 SARS-CoV-2
K1 covid 19
K1 diphtheria tetanus pertussis vaccine
K1 influenza vaccines
K1 maternal immunization
K1 passive immunization
K1 pregnancy
AB The COVID-19 pandemic has raised questions about the possible cross immunity resulting from common vaccination programs and SARS-CoV-2 infection. Therefore, the Spanish Obstetric Emergency group performed a multicenter prospective study on the vaccination status of Influenza and Tdap (diphtheria, tetanus and pertussis vaccine boost administered in adulthood) in consecutive cases of SARS-CoV-2 infection in a pregnancy cohort, in order to assess its possible association with the clinical presentation and severity of symptoms of SARS-CoV-2 infection, as well as to determine the factors that may affect vaccination adherence. A total of 1150 SARS-CoV-2 positive pregnant women from 78 Spanish hospitals were analyzed: 183 had not received either vaccine, 23 had been vaccinated for Influenza only, 529 for Tdap only and 415 received both vaccines. No association was observed between the vaccination status and the clinical presentation of SARS-CoV-2 infection and/or the severity of symptoms. However, a lower adherence to the administration of both vaccines was observed in the Latin-American subgroup. Based on the results above, we reinforce the importance of maternal vaccination programs in the actual pandemic. Health education campaigns should be specially targeted to groups less likely to participate in these programs, as well as for a future SARS-CoV-2 vaccination campaign.
SN 2076-393X
YR 2021
FD 2021-01-08
LK http://hdl.handle.net/10668/16952
UL http://hdl.handle.net/10668/16952
LA en
DS RISalud
RD Apr 5, 2025