RT Journal Article
T1 Cruciferous Vegetable Intake and Bulky DNA Damage within Non-Smokers and Former Smokers in the Gen-Air Study (EPIC Cohort).
A1 Peluso, Marco
A1 Munnia, Armelle
A1 Russo, Valentina
A1 Galli, Andrea
A1 Pala, Valeria
A1 Schouw, Yvonne T van der
A1 Schulze, Matthias B
A1 Weiderpass, Elisabete
A1 Tumino, Rosario
A1 Saieva, Calogero
A1 Exezarreta Pilar, Amiano
A1 Aune, Dagfinn
A1 Heath, Alicia K
A1 Aglago, Elom
A1 Agudo, Antonio
A1 Panico, Salvatore
A1 Petersen, Kristina Elin Nielsen
A1 Tjønneland, Anne
A1 Cirera, Lluis
A1 Rodriguez-Barranco, Miguel
A1 Katzke, Verena
A1 Kaaks, Rudolf
A1 Ricceri, Fulvio
A1 Milani, Lorenzo
A1 Vineis, Paolo
A1 Sacerdote, Carlotta
K1 B(a)P-adducts
K1 DNA damage
K1 EPIC
K1 bulky oxidative lesions
K1 cruciferous vegetables
K1 diet
AB Epidemiologic studies have indicated that cruciferous vegetables can influence the cancer risk; therefore, we examined with a cross-sectional approach the correlation between the frequent consumption of the total cruciferous vegetables and the formation of bulky DNA damage, a biomarker of carcinogen exposure and cancer risk, in the Gen-Air study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. DNA damage measurements were performed in the peripheral blood of 696 of those apparently healthy without cancer controls, including 379 never-smokers and 317 former smokers from seven European countries by the 32P-postlabeling assay. In the Gen-Air controls, the median intake of cruciferous vegetables was 6.16 (IQR 1.16−13.66) g/day, ranging from 0.37 (IQR 0−6.00) g/day in Spain to 11.34 (IQR 6.02−16.07) g/day in the UK. Based on this information, participants were grouped into: (a) high consumers (>20 g/day), (b) medium consumers (3−20 g/day) and (c) low consumers (20 g/day), (b) medium consumers (3−20 g/day) and (c) low consumers (
PB MDPI AG
YR 2022
FD 2022-06-13
LK http://hdl.handle.net/10668/21481
UL http://hdl.handle.net/10668/21481
LA en
NO Peluso M, Munnia A, Russo V, Galli A, Pala V, Schouw YTV, et al.  Cruciferous Vegetable Intake and Bulky DNA Damage within Non-Smokers and Former Smokers in the Gen-Air Study (EPIC Cohort). Nutrients. 2022 Jun 15;14(12):2477.
DS RISalud
RD Apr 18, 2025