RT Journal Article T1 Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case-Control Study. A1 Romero-Gómez, Benjamín A1 Guerrero-Alonso, Paula A1 Carmona-Torres, Juan Manuel A1 Pozuelo-Carrascosa, Diana P A1 Laredo-Aguilera, José Alberto A1 Cobo-Cuenca, Ana Isabel K1 health K1 hypothyroidism K1 quality of life K1 thyroid hormone K1 women AB The use of levothyroxine is not always related to the elimination of the symptoms of hypothyroidism. The aim of this study is to compare the health-related quality of life (HRQOL) of a group of hypothyroid women under levothyroxine treatment with that of a group of non-hypothyroid women. A case-control study was performed. We used convenience sampling. The case group consisted of 152 levothyroxine-treated hypothyroid women; the control group consisted of 238 women without hypothyroidism disorders. All of the participants were euthyroid according to the clinical practice guidelines. We used as instruments the Short Form-12 questionnaire (SF-12v1) and a sociodemographic questionnaire. Hypothyroid women scored significantly lower in HRQOL in SF-12v1 mental and physical components than the control group (mental component summary: 41.23 ± 12.12 vs. 46.45 ± 10.22, p Despite being euthyroid, women with hypothyroidism showed a poorer quality of life than women without hypothyroidism. Health professionals need to assess the HRQOL of women with hypothyroidism. Further research on HRQOL and hypothyroidism is needed. SN 2077-0383 YR 2020 FD 2020-11-27 LK https://hdl.handle.net/10668/28229 UL https://hdl.handle.net/10668/28229 LA en DS RISalud RD Apr 8, 2025